![]() Whether any difference exists in the impact of paroxysmal versus non-paroxysmal AF on post-TMVR outcomes remains a subject of interest. Previous studies have shown that non-paroxysmal AF is associated with higher rate of stroke and mortality when compared to paroxysmal AF ( 8). Patients with degenerative MR and AF had higher risks of stroke, bleeding, death and HF hospitalizations, after TMVR. Almost half of the patients with degenerative MR have AF at 10 years ( 7). It has been categorized as paroxysmal (returns to sinus rhythm within 7 days), non-paroxysmal (returns to sinus rhythm after 7 days), or permanent (does not return to sinus rhythm) ( 6). The MitraClip ® device system is now approved for repair of both degenerative and functional MR in US and has been proven to be effective in reducing MR, symptoms of heart failure, and left ventricular remodeling ( 3, 4).Ītrial fibrillation (AF) significantly increases the risk of cardioembolic events and heart failure ( 5). ![]() Transcatheter mitral valve repair (TMVR) has emerged as a promising treatment option for symptomatic patients with chronic severe primary mitral regurgitation for patients at higher surgical risk ( 1, 2). Keywords: Atrial fibrillation (AF) paroxysmal transcatheter mitral valve repair (TMVR) mortality Future studies exploring the effect of type of atrial fibrillation on long term outcomes are needed. paroxysmal AF.Ĭonclusions: Inpatient outcomes and readmissions were similar in patient with paroxysmal and non-paroxysmal atrial fibrillation in this study. ![]() Similarly, no differences were noted in the odds of cardiac readmissions (OR 1.38 95% CI: 0.83–2.28), non-cardiac readmissions (OR 0.80 95% CI: 0.49–1.32) and discharge to skilled nursing/short term care (OR 1.24 95% CI: 0.66–2.36) in those with non-paroxysmal vs. As compared to paroxysmal AF, those with non-paroxysmal AF had comparable odds of composite outcome of stroke, readmission, or mortality (OR 1.31 95% CI: 0.77–2.23), as well as stroke (OR 0.43 95% CI: 0.10–1.78), or mortality (OR 0.54 95% CI: 0.21–1.37), in patients undergoing TMVR. Patients with non-paroxysmal AF were older than paroxysmal AF (82.53 vs. Of these, 510 (weighted N=995) patients had non-paroxysmal AF and 403 (weighted N=755) had paroxysmal AF. Results: A total of 913 (weighted N=1,750) TMVR hospitalizations from NRD for year 2016 were included. Statistical Analysis System (SAS) software 9.4 was used to conduct the analysis. The association between type of AF and mortality, stroke, readmission (cardiovascular and non-cardiovascular readmissions) and composite outcome (mortality, inpatient stroke or 30-day readmissions) was analyzed using multivariable logistic regression. Methods: Patients 18 years or older who underwent TMVR procedure in 2016 and had a concurrent ICD-10 diagnosis of either paroxysmal or non-paroxysmal AF were included from Nationwide Readmission Database (NRD). However, the impact of type of AF in patients undergoing transcatheter mitral valve (MV) repair remains uncertain. The development of atrial fibrillation (AF) in degenerative mitral regurgitation (MR) can be a sign of progression of MR and associated with adverse outcomes. Background: To study the impact of type of atrial fibrillation on outcomes following transcatheter mitral valve repair.
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